To develop a patientbased measure of walking ability in ms. Gait impairment is commonly in people with multiple sclerosis ms. The 12item multiple sclerosis walking scale msws12 is a patientreported outcome measure that assesses patients perception of the impact of multiple sclerosis ms on walking ability, but cannot be used in costeffectiveness or costutility analyses which require a healthutility score to calculate qualityadjusted lifeyears. Groupbased individualized comprehensive core stability. Original article identifying an important change estimate for the multiple sclerosis walking scale12 by lahar mehta, manjit mcneill, jeremy hobart, kathleen w wyrwich, jiatling poon, priscilla auguste, john zhong and jacob elkins. For example, the 12item multiple sclerosis walking scale msws12 measures the patientreported impact of the disease on walking ability. Further validation of multiple sclerosis walking scale12. Effects of an individual 12week communitylocated start.
Six ms outpatient clinics across italy enrolled subjects between june 20 and. The findings have implications for the design of future studies of progressive multiple sclerosis, because lower than expected progression rates might have affected our ability to detect clinical change. This pragmatic randomized controlled study investigated the effects of a remotely supervised communitylocated starttorun program on physical and. Evaluation of the multiple sclerosis walking scale12.
Multiple sclerosis ms is a chronic, progressive disorder of the central nervous system that commonly affects young adults. It is well established that persons with ms have greater gait variability compared to age and gender. Effect of dronabinol on progression in progressive. Validation of patient determined disease steps pdds. Mapping the 12item multiple sclerosis walking scale to. Pdf italian validation of the 12item multiple sclerosis. This study aimed to profile gait pathology in gaitimpaired patients with ms using comprehensive 3d gait analysis and. To date, there is limited evidence regarding the validity of pdds scores, despite its sound conceptual development and broad inclusion in ms research. Preliminary psychometric evaluation data quality, scaling assumptions, acceptability, reliability, validity was undertaken in the data. Hutchinson, confirming the validity and responsiveness of the multiple sclerosis walking scale12 msws12, neurology, vol. Evaluation of the sixminute walk in multiple sclerosis. The patient determined disease steps pdds is a promising patientreported outcome pro of.
Longitudinal changes in selfreported walking ability in. It consists of 12 questions concerning the limitations to walking due to ms during the past 2 weeks. Gait dysfunction is a common and relevant symptom in multiple sclerosis ms. The aim of this study was to evaluate the safety, feasibility and preliminary effects of a highintensity rehabilitative taskoriented circuit training toct in a sample of multiple sclerosis ms subjects on walking competency, mobility, fatigue and healthrelated quality of life hrqol. The 12item multiple sclerosis walking scale msws12 is a selfreport measure of the impact of ms on the individuals walking ability. Multiple sclerosis walking scale12 and oxygen cost of. Severity scale, walking ability multiple sclerosis walking scale 12 and healthrelated quality of life multiple sclerosis impact scale 29 were included. The scale has not been independently validated for use in differing ms populations. The widelyused 12question multiple sclerosis walking scale msws12v1 is a patientreported measure of walking ability in multiple sclerosis ms. Gait dysfunction in ms is distinguished by decreased gait speed, walking endurance, step length, cadence and joint motion, as well as increased metabolic cost of walking and increased variability of gait. Gait impairment is reported by 85% of patients with multiple sclerosis ms as main complaint.
Measuring the impact of ms on walking ability neurology. To examine the association between multiple sclerosis walking scale12 msws12 scores and spatiotemporal parameters of gait as indicators of gait quality among ambulatory persons with multiple sclerosis ms. There are relatively few standard, objective measures for studying physical function among older adults with multiple sclerosis ms, yet such measures are necessary considering the shift in prevalence and associated consequences of both ms and older age on physical function. Identifying an important change estimate for the multiple.
This study examined the validity of the pdds based on 1 the association with. Ecological validity of walking capacity tests following. Achievement and maintenance of optimal function are essential in a progressive disease such as ms. Background walking capacity tests are commonly used to evaluate interventions aiming at reducing walking impairment in people with multiple sclerosis pwms. However, their ecological validity has recently been questioned. The multiple sclerosis walking scale is a selfassessment scale which measures the impact of ms on walking. One patient no longer needed to use a cane as a walking aid after 2 weeks of treatment and this was maintained until the end of the followup period. Subjects assessments were delivered at baseline t0, after toct t1 and 3 months of homebased exercise program t2. Multiple sclerosis impact scale msis29 the following questions ask for your views about the impact of ms on your daytoday life during the past two weeks for each statement, please circle the one number that best describes your situation please answer all questions in the past two weeks, how much has.
A taskoriented circuit training in multiple sclerosis. The 12item multiple sclerosis walking scale msws 12 what does this author special investigating alternative medicine but in many cases most patients to ever be truly better improving the patient has been brought on by facial movements through even with associated with multiple sclerosis before contract. Cohort study comparing the berg balance scale and the mini. More recently, selfreport measures such as the ms walking scale12 msws12 have been validated, allowing integration of the patients perception of walking performance and limitations into outcome measurement. The 12item multiple sclerosis walking scale msws12 has been validated against selfreport and clinical markers, but has not been validated with a.
To assess the correlation of 6mw to subjective measures of fatigue. A change will be indicated by a reduction or increase. The aim of the present study was to investigate the ecological validity of the 2 and 6minutes walking tests 2mwt and 6mwt and the timed 25. In a version 2, three items are scored, and nine items are. Research article open access a taskoriented circuit.
Hobart jc, riazi a, lamping dl, fitzpatrick r, thompson aj. Preliminary validation of the short physical performance. Possible secondary outcomes for the definitive trial. We examined the quality of the msws12 using an item response theory model, the graded response model grm. An equation for mapping the msws12 to the eq5d was previously developed and validated using a north american research committee on ms narcoms registry cohort. Forty pwms were randomly assigned to the dtt or smt groups. Objective we studied longitudinal changes in walking ability using the msws. Walking impairment is a common marker of disease progression in individuals with multiple sclerosis ms. There are many measures of walking impairment that have been included in research and clinical practice such as the expanded disability status scale edss, timed walk tests e.
Confirming the validity and responsiveness of the multiple. Patientreported outcomes are also useful to inform disease severity. Healthrelated quality of life euroqol eq5d5l and the 29item multiple sclerosis impact scale msis29 version 2. The 12item multiple sclerosis walking scale msws12 is a new, selfrated measure of walking ability. Correlations between inertial body sensor measures and. Multiple sclerosis ms is a demyelinating disease of the central nervous system characterized by episodic decline in various neurologic functions. Evaluation of the sixminute walk in multiple sclerosis subjects and healthy controls myla d goldman1, ruth ann marrie 2and jeffrey a cohen objective to assess the characteristics of the 6min walk 6mw in multiple sclerosis ms subjects of varied disability, and controls. Multiple sclerosis walking scale12, translation, adaptation and validation for the persian language population.
The aim of this study was to examine the reliability and validity of the msws12 in persian speaking patients with ms. The aim was to compare the effectiveness of dualtask training dtt compared to single mobility training smt on dualtask walking, mobility and cognition, in persons with multiple sclerosis pwms. The multiple sclerosis walking scale12 msws12 is a multiitem rating scale used to assess the perspectives of patients about the impact of ms on their walking ability. Each item can be answered with 5 options, with 1 meaning no limitation and 5 extreme limitation. The 12item ms walking scale msws12 assesses patients measurement of walking quality. A total of 625 unique dutch multiple sclerosis ms patients were included. Original article identifying an important change estimate. Multiple sclerosis and nmosds can be distinguished from other disorders that cause myelopathy by results from laboratory and radiological investigations. We undertook a preliminary examination of the construct validity of short.
However, limitations in the sensitivity and specificity of spinal cord. Should we routinely monitor walking in patients with. Walkingmultiple sclerosis walking scale12 item msws12 version 2. Improving ambulation in multiple sclerosis touchneurology.
Background patientreported outcomes are increasingly used to understand the clinical meaningfulness of multiple sclerosis disability and its treatments. Pdf multiple sclerosis walking scale12, translation. Eightytwo persons with multiple sclerosis wore an accelerometer as a measure of sedentary time minday and completed measures of disability status selfreported expanded disability status scale, walking performance timed 25foot walk and 6min walk, and cognitive function symbol digit modalities test. Our results show that dronabinol has no overall effect on the progression of multiple sclerosis in the progressive phase. The higher the scorepercentage, the greater the perceived impact ms is having on walking ability. The original scoring provides options 15 for each item, with 1 meaning no limitation and 5 meaning extreme limitation on the gaitrelated item. Gait variability, that is, fluctuations in movement during walking, is an indicator of walking function and has been associated with various adverse outcomes such as falls. Profiling walking dysfunction in multiple sclerosis.
One hundred fortynine patients in the community and 53 hospital outpatients with ms completed the msws12 and other outcome measures. One study in progressive ms patients found that change in walking speed was significantly related to longterm after 5 years of more selfreported impact of the disease and selfreported walking limitations. The multiple sclerosis walking scale msws12 is the predominant patientreported measure of multiple sclerosis ms elated walking ability, yet it had not been analyzed using item response theory irt, the emerging standard. In this paper, current research concerning gait variability in persons with multiple sclerosis ms is discussed. The patient determined disease steps pdds is a promising patientreported outcome pro of disability in multiple sclerosis ms. Twelve item ms walking scale msws 12 graph patient progress over time twelve item ms walking scale use the graphs below to plot the percentage score from the questionnaire at each visit. Mapping of multiple sclerosis walking scale msws12 to. The psychometric properties of the msws12 were excellent, and in. Multiple sclerosis rehabilitation physiotherapy treatment. The aim of this study was to crossculturally adapt and validate the msws12 for the italian population with ms.
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